07-24-2026, 01:41 AM
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We designed and conducted the DESIRE trial (DExmedetomidine for Sepsis in ICU Randomized Evaluation trial) to test a hypothesis that dexmedetomidine may improve clinical outcome and has these organ protective effects on septic patients.&We designed and conducted the DESIRE trial (DExmedetomidine for Sepsis in ICU Randomized Evaluation trial) to test a hypothesis that dexmedetomidine may improve clinical outcome and has these organ protective effects on septic patients.$In this 2-for-1 episode, Jim Miller highlights the DESIRE study as a Trial of the Week, before Michael Liu highlights his experience and advice with in-flight medical emergencies.&Trial of the Week: DESIRE & In-Flight Medical Emergencies References Special Guests: Jim Miller, PharmD, BCCCP Michael Liu, PharmD, MBA, BCCCP, BCNSP, BCPS%Methods This study involved a post-hoc analysis of data from the Dexmedetomidine for Sepsis in the ICU Randomized Evaluation (DESIRE) trial. The patients were categorized based on median age into elderly and younger groups.^Effect of Dexmedetomidine on Mortality and Ventilator-Free Days in Patients Requiring Mechanical Ventilation With Sepsis: A Randomized Clinical Trial Kawazoe Y. JAMA. Published online March 21, 2017 Clinical Question In ventilated patients with sepsis, does a sedation strategy with dexmedetomidine compared with no dexmedetomidine improve mortality and number of ventilator-free days? Design`Methods: This study involved a post-hoc analysis of data from the Dexmedetomidine for Sepsis in the ICU Randomized Evaluation (DESIRE) trial. The patients were categorized based on median age into elderly and younger groups.
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We designed and conducted the DESIRE trial (DExmedetomidine for Sepsis in ICU Randomized Evaluation trial) to test a hypothesis that dexmedetomidine may improve clinical outcome and has these organ protective effects on septic patients.&We designed and conducted the DESIRE trial (DExmedetomidine for Sepsis in ICU Randomized Evaluation trial) to test a hypothesis that dexmedetomidine may improve clinical outcome and has these organ protective effects on septic patients.$In this 2-for-1 episode, Jim Miller highlights the DESIRE study as a Trial of the Week, before Michael Liu highlights his experience and advice with in-flight medical emergencies.&Trial of the Week: DESIRE & In-Flight Medical Emergencies References Special Guests: Jim Miller, PharmD, BCCCP Michael Liu, PharmD, MBA, BCCCP, BCNSP, BCPS%Methods This study involved a post-hoc analysis of data from the Dexmedetomidine for Sepsis in the ICU Randomized Evaluation (DESIRE) trial. The patients were categorized based on median age into elderly and younger groups.^Effect of Dexmedetomidine on Mortality and Ventilator-Free Days in Patients Requiring Mechanical Ventilation With Sepsis: A Randomized Clinical Trial Kawazoe Y. JAMA. Published online March 21, 2017 Clinical Question In ventilated patients with sepsis, does a sedation strategy with dexmedetomidine compared with no dexmedetomidine improve mortality and number of ventilator-free days? Design`Methods: This study involved a post-hoc analysis of data from the Dexmedetomidine for Sepsis in the ICU Randomized Evaluation (DESIRE) trial. The patients were categorized based on median age into elderly and younger groups.